1. Murders 1/2 Whoever committed them knew the area because he allowed the women to choose the location. Is there empirical evidence for that? I'm not sure there is, but perhaps you can enlighten us.
There is evidence that both the women were actively soliciting at the time they met their killer, and a lack of evidence that the killer and victims knew each other before the fatal meeting. That suggests to me that the killer acted as if he was a customer when meeting the women, and it was the women who led the customers to the locations they preferred. I think in the first murder he was overeager, and in the second murder, since it takes place far further south than any other Canonical, suggests a broader understanding by the killer of where the less travelled streets are in East London in general, not just that little square of land where many assaults took place.
2. But if we accept, for the sake of argument, that this were the case, then what you seem to be suggesting is that Jack had an encyclopaedic knowledge of Spitalfields and Whitechapel, so it didn't matter where the women took him, he would know the best escape route.
I suggest that the killer of the first 2 victims seems to have a sound understanding of the area, I wouldn't use, nor did I use, your adjective when describing that knowledge.
3. I would argue that there is no magical escape route from either Bucks Row or Hanbury Street. As you say above about Berners Street, you stick your head out of the door of Hanbury Street and if the coast is clear, you turn either right or left. In Bucks Row you are already in the Street, so it's just a case of look left, look right, walk smartly away. The option of going round the Board School into Winthrop Street provides an almost immediate opportunity to branch off, but there would have been a greater risk of detection there.
Killing in In Bucks Row was a mistake for the killer, I agree, in the middle of an open-ended street, (which may suggest his naiveté as a killer), but in Hanbury you have fences that one might easily hop in addition to the street access. There is no evidence that he left via the passage through the house, so its at least possible he left over some fences. Which fences to take, and which direction to go to find a quiet lane to slip away on is why I suggest some local knowledge.
4. Murders 3/4/5 May have been pre-planned and this suggests the killer did not know the area. You've lost me there. How do you plan an attack in an area you don't know?
Im playing Devils Advocate here, but for the sake of the argument its worth pointing out that as of this minute we have no viable reasons that adequately explain why Liz Stride was attacked at that location, why Kate was in Mitre Square at all, and how someone attacks Mary in her own bed. That leaves open all sorts of motive possibilities, and possibilities that the killer(s) knew those victims, and knew where he(they) were going to kill the women. So they could have familiarized themselves with those specific locations, which suggests nothing of any broader knowledge of the area.
Even if the killer(s) didn't know where they were going to kill the women, its still a fact that no-one saw any suspect leaving any of these crimes scenes,....(unless it was the Nichols site

Im a stickler on this point....and its one that allows for tangential observations,.... and that is that the probable motives for the murders of Canonical 3, 4 and 5 have not been revealed by the historical review of the known facts. The first 2 seem to be the random assault type, select any target that is out working the streets, the more feeble the better,... pose as a client... and attack when their guard is down. There is the eerily similar methodology and injury present in both attacks that supports a single killer as well.
After many years of study Ive concluded that the characteristics of the killer(s) who committed the so-called Jack the Ripper murders is never more evident than in the first 2 canonical deaths. Which, for me, suggests that we need to keep looking for motives that might explain the others, rather than just blindly accept the many theories that do not explain those often dramatic differences in victimology, methodology and activity.
Cheers
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