I recently found out that in January and February of 1889, something titled "Jack the Ripper" played at a theatre in Aspen, Colorado. Unfortunately, these references were only one line display ads, so I have no idea if it was a melodrama or comedy. (I'll post the citations tomorrow, but the database was Colorado Historic Newspapers.)
Can't help wondering if this might be one of the earliest dramas about the Ripper?
: Jack the Ripper plays shuffleboard. -- Happy Birthday, Wanda June
by Kurt Vonnegut, c.1970.